Tadalafil 5mg: A Key to Unlock What?
Gui í a de Salud Masculina
tadalafil (tadalafil) 5mg is a drug used to treat erectile dysfunction (ED) and lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). Here are the details:
I. Pharmacological action
1 、Mechanism of action on erectile dysfunction
Tadalafil is a phosphodiesterase 5 (PDE5) inhibitor. During sexual stimulation, nerve endings and endothelial cells in the penile cavernous body release nitric oxide (NO). NO activates guanylate cyclase, which increases the level of cyclic guanosine monophosphate (cGMP), resulting in smooth muscle relaxation and blood flow into the penile cavernous body, causing an erection.
Tadalafil helps to maintain penile erectile function by inhibiting PDE5, reducing the degradation of cGMP and maintaining a high level of cGMP in the penile sponge.
2 、Mechanism of action on benign prostatic hyperplasia
There is PDE5 in the prostate and bladder neck. Tadalafil can relax the smooth muscle of the prostate and bladder neck and improve the lower urinary tract symptoms caused by benign prostatic hyperplasia, such as dysuria, frequent urination, urgent urination and so on.
II. Usage amount
1 、Treatment of erectile dysfunction
For most patients, the initial dose of tadalafil is 10mg before sex, but 5mg can also be taken regularly once a day. This low-dose regular use may help to improve the patient's spontaneous erectile function and may be well tolerated for long-term use.
2 、Treatment of benign prostatic hyperplasia
-the recommended dose is 5mg once a day, which can be adjusted according to the symptoms and tolerance of the patient.
Third, adverse reactions
1 、Common adverse reactions
HeadacheThis is a common adverse reaction, which may be related to the vasodilator effect of the drug.
DyspepsiaInclude symptoms such as stomach discomfort, abdominal distension and nausea, usually mild to moderate.
Back painSome patients may have back pain after medication, but the exact mechanism is not completely clear.
MyalgiaMuscle pain is also one of the possible adverse reactions.
2 、Rare adverse reactions
-facial flushing, nasal congestion and visual abnormalities (such as blurred vision, color vision changes, etc.) may occur, but the incidence of these adverse reactions is relatively low.
IV. matters needing attention
1 、Cardiovascular system
Tadalafil has a mild vasodilation effect, and tadalafil is strictly prohibited for patients who are taking nitrates (such as nitroglycerin, isosorbide mononitrate, etc.), as the combination of the two may lead to severe hypotension.
For patients at risk of cardiovascular disease, cardiovascular function should be evaluated and medication should be taken with caution before using tadalafil.
2 、Other aspects
Tadalafie is not suitable for women and children.
-if there is an abnormal erection of the penis (lasting for more than 4 hours), you should seek medical advice immediately, as this may lead to permanent erectile dysfunction.