Tadalafil 40 mg is used mainly for two main purposes:

1. Treatment of erectile dysfunction (ED)

Mechanism for action:

-Tadalafil inhibits the enzyme phosphodiesterase type 5 (PDE5). In the penis, relaxation of smooth muscles is essential for proper blood flow and obtaining and maintaining erection. PDE5 is responsible for degrading cyclic monophosphate guanosin (cGMP), an important mediator in vascular relaxation. By inhibiting PDE5, tadalafil increases cGMP levels, which promotes relaxation of smooth penis muscles and allows better blood flow to it, facilitating erection.

Effectiveness:

-help men with SD get enough erections for vaginal sex. The 40 mg dose may be an option for patients who do not respond adequately at lower doses or for whom a higher dose has been determined on the basis of medical evaluation to be appropriate.

2. Treatment of pulmonary arterial hypertension (HTAP)

Mechanism of action in HTAP:

-in pulmonary arterial hypertension, the blood vessels in the lungs are narrowed, which increases blood pressure in the lungs. Tadalafil works by relaxing the smooth muscles of pulmonary blood vessels, which helps to dilate them and, consequently, reduce blood pressure in the lungs.

Efficacy in HTAP:

-it can improve the functional capacity and quality of life of patients with HTAP, relieving associated symptoms such as fatigue, shortness of breath and limited exercise capacity.

It is important to note that tadalafil should be prescribed by a doctor and its use must be accompanied by adequate medical evaluation, as it may have interactions with other medicines and is not suitable for all patients. In addition, in some cases, it may cause side effects such as headache, dizziness, indigestion, among others.

Tadalafil 40 mg (trade name: Cialis) is a medication used to treat erectile dysfunction in men. It works by relaxing the muscles of the penis, allowing blood flow to increase and leading to an erection.

Tadalafil 40 mg may be taken as needed, but it should not be taken more than eleven per day. The recommended starting dose is 20 mg, which can be increased to 40 mg if necessary. It should be taken approximately 30 minutes before sexual activity.

Common side effects of tadalafil 40 mg include headache, flushing, dizziness, and muscle pain. If you experience any serious side effects such as vision changes or chest pain, seek medical attention immediately.

It is important to discuss your medical history with your doctor before taking tadalafil 40 mg, including any medications you are taking or have taken in the past. This medication should not be taken by people who have certain medical conditions or who are taking certain medications.