Tadalafil: Unveiling Its Mysterious Features
Gui í a de Salud Masculina
Tadarafi (tadalafil).
I. basic information
1 、Drug type
Tadalafil is a type 5 phosphodiesterase (PDE5) inhibitor.
2 、Indication
Male erectile dysfunction (ED)
-by inhibiting PDE5, reducing the degradation of cyclic guanosine monophosphate (cGMP), relaxing the smooth muscle in the penile sponge and filling the blood, thus improving the erectile function.
Pulmonary hypertension (PAH)
It can dilate pulmonary vessels, reduce pulmonary vascular resistance, and improve the exercise ability and hemodynamic indexes of patients with pulmonary hypertension.
II. Usage amount
1 、Usage and dosage of therapeutic ED
When taking 10mg on demand, it is recommended that the initial dose be taken before sex. Depending on the efficacy and tolerance of the individual, the dose can be increased to 20mg or reduced to 5mg. The maximum frequency of taking the drug is once a day.
For most patients, the recommended maximum frequency of administration is once a day.
-there are also regular treatments, such as daily small doses (such as 2.5mg or 5mg), which may have a better long-term effect on improving erectile function in some patients.
2 、Usage and dosage of therapeutic PAH
-the recommended dose is 40mg (once daily).
Third, adverse reactions
1 、Common adverse reactions
Headache: it is a common adverse reaction, which is generally mild to moderate and may be alleviated gradually with the time of medication.
DyspepsiaIncluding stomach discomfort, stomach distension, nausea and other symptoms.
Back painSome patients may experience low back pain.
MyalgiaMuscle pain is also one of the possible adverse reactions.
2 、Other adverse reactions
-there may be flushing, nasopharyngitis, respiratory tract infection, etc., a small number of patients may have visual abnormalities, dizziness and other conditions, but relatively uncommon.
IV. matters needing attention
1 、Patients with cardiovascular disease
-for patients with cardiovascular diseases (such as unstable angina pectoris, recent myocardial infarction, etc.), it is necessary to carefully assess the risk when using tadalafil, because sexual activity itself has certain requirements on the cardiovascular system. Tadalafil may affect cardiovascular parameters such as blood pressure.
2 、Drug interaction
-it is forbidden to use in conjunction with organic nitrates (such as nitroglycerin), as the combination of the two may cause severe hypotension.
-when used in combination with alpha-blockers (such as tamsulosin and other drugs used to treat benign prostatic hyperplasia), the risk of hypotension may be increased. If necessary, the dose should be carefully adjusted and blood pressure should be closely monitored.